Denagard® Premix (Tiamulin)
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Oral antibiotic intended for preventive and therapeutic in feed medication in pigs and poultry.
Description and Composition
DENAGARD Premixes are manufactured with a gel-coated tiamulin hydrogen fumarate concentrate. Gel-coating of the active substance improves stability, reduces dustiness and ensures consistent mixing and dispersal in finished feed. DENAGARD Premix for medicated feed contains 20 mg (2% Premix) or 100 mg (10% Premix) tiamulin hydrogen fumarate per gram of product.
Tiamulin is a bacteriostatic agent, belonging to the group of pleuromutilins. It has a wide spectrum of activity but is particularly active against Brachyspira, Lawsonia and Mycoplasma species. Unlike other antibiotics intended for in-feed medication, tiamulin belongs to a category of antibiotics which is not used in human medicine.
Treatment and control of Mycoplasma infections (enzootic pneumonia, chronic respiratory disease) and porcine respiratory disease complex. It has a synergistic activity with tetracyclines against other primary (A.pleuropneumoniae, B.bronchiseptica) and secondary (P.multocida) respiratory pathogens.
DENAGARD is particularly indicated for the control, prevention and treatment of swine dysentery (B.hyodysenteriae), porcine colonic spirochaetosis (B.pilosicoli)and porcine proliferative enteropathy (L.intracellularis).
Dosage and administration
- Control of swine dysentery: 1.5 – 2 mg tiamulin hydrogen fumarate/kg bodyweight (equivalent to an inclusion level of 30-40 ppm in the finished feed)
- Treatment of swine dysentery and ileitis: 6 – 8 mg tiamulin hydrogen fumarate /kg bodyweight (equivalent to an inclusion level of 100-150 ppm in the finished feed)
- Control of mycoplasmal pneumonia: 2 mg tiamulin hydrogen fumarate/kg bodyweight (equivalent to an inclusion level of 40 ppm in the finished feed)
- Treatment of PRDC (porcine respiratory disease complex): 6 – 10 mg/kg bodyweight (equivalent to an inclusion level of 100-200 ppm in the finished feed)
- Prevention and treatment of chronic respiratory disease (CRD) and infectious synovitis in broilers, replacement pullets, laying and breeding hens: 25-50 mg/kg bodyweight per day (25-50 g Denagard 10% Premix / 100 kg bodyweight).
- Prevention and treatment of infectious sinusitis and air sacculitis in young poults and breeding turkeys: 25-50 mg/kg bodyweight per day (25-50 g Denagard 10% Premix / 100 kg bodyweight).
Withdrawal periods according to national registrations.
Special Precautions and Warnings
Do not administer the ionophore anticoccidials salinomycin, monensin or narasin to poultry and pigs receiving therapeutic doses of DENAGARD. Pigs and poultry should not receive products containing ionophores during or for at least seven days before or after treatment with DENAGARD.
Formulations and Packages
DENAGARD 2% and 10% Premix is available in bags of 1kg (10% Premix only), 5 kg and 25kg bags.
Please note that not all products listed within this site may be available in all countries. Also, prescribing information and indications for products may differ from country to country, so please consult your local veterinarian for local prescribing and any other information you may be interested in.
Headquartered in Basel, Switzerland, and present in almost 40 countries, Novartis Animal Health employs approximately 2,900 associates worldwide.
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Visit our international Denagard website to learn more about one of the most potent antibiotics against the key enteric and respiratory infections affecting pigs and poultry..