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Denagard® Premix (Tiamulin)
Product information on this website is for Non-U.S. residents only and is provided by Novartis Animal Health Inc. for general purposes only. Many veterinary products listed are available upon prescription only, and not all such products may be available in all countries. The product information is not intended to provide complete medical information. SHOULD YOUR ANIMAL HAVE A MEDICAL CONDITION, PROMPTLY SEE YOUR OWN VETERINARIAN. WE DO NOT OFFER PERSONALIZED MEDICAL DIAGNOSIS OR ANIMAL-SPECIFIC TREATMENT ADVICE. You should always obtain complete medical information about your veterinary product prescription (including their beneficial medical uses and possible adverse effects) by discussing the appropriate use of any veterinary product directly with the prescribing veterinarian.
Veterinary professionals may obtain complete medical information from the product's information leaflet. Information on these products may vary by country. Animal owners and veterinarians should check with local medical resources and regulatory authorities for information appropriate to their country. In addition, current regulations in many countries limit (or even prohibit in some instances) the ability of Novartis Animal Health Inc. to provide information and/or to respond directly to questions regarding its prescription products. Novartis Animal Health Inc., however, will respond to inquiries from and provide information to your qualified health care professional in accordance with local regulations.
Premix
Product Type
Oral antibiotic intended for preventive and therapeutic in feed medication in pigs and poultry.
Description and Composition
DENAGARD Premixes are manufactured with a gel-coated tiamulin hydrogen fumarate concentrate. Gel-coating of the active substance improves stability, reduces dustiness and ensures consistent mixing and dispersal in finished feed. DENAGARD Premix for medicated feed contains 20 mg (2% Premix) or 100 mg (10% Premix) tiamulin hydrogen fumarate per gram of product.
Properties
Tiamulin is a bacteriostatic agent, belonging to the group of pleuromutilins. It has a wide spectrum of activity but is particularly active against Brachyspira, Lawsonia and Mycoplasma species. Unlike other antibiotics intended for in-feed medication, tiamulin belongs to a category of antibiotics which is not used in human medicine.
Indications
Treatment and control of Mycoplasma infections (enzootic pneumonia, chronic respiratory disease) and porcine respiratory disease complex. It has a synergistic activity with tetracyclines against other primary (A.pleuropneumoniae, B.bronchiseptica) and secondary (P.multocida) respiratory pathogens.
DENAGARD is particularly indicated for the control, prevention and treatment of swine dysentery (B.hyodysenteriae), porcine colonic spirochaetosis (B.pilosicoli)and porcine proliferative enteropathy (L.intracellularis).
Dosage and administration
Pigs:
- Control of swine dysentery: 1.5 – 2 mg tiamulin hydrogen fumarate/kg bodyweight (equivalent to an inclusion level of 30-40 ppm in the finished feed)
- Treatment of swine dysentery and ileitis: 6 – 8 mg tiamulin hydrogen fumarate /kg bodyweight (equivalent to an inclusion level of 100-150 ppm in the finished feed)
- Control of mycoplasmal pneumonia: 2 mg tiamulin hydrogen fumarate/kg bodyweight (equivalent to an inclusion level of 40 ppm in the finished feed)
- Treatment of PRDC (porcine respiratory disease complex): 6 – 10 mg/kg bodyweight (equivalent to an inclusion level of 100-200 ppm in the finished feed)
Chickens:
- Prevention and treatment of chronic respiratory disease (CRD) and infectious synovitis in broilers, replacement pullets, laying and breeding hens: 25-50 mg/kg bodyweight per day (25-50 g Denagard 10% Premix / 100 kg bodyweight).
Turkeys:
- Prevention and treatment of infectious sinusitis and air sacculitis in young poults and breeding turkeys: 25-50 mg/kg bodyweight per day (25-50 g Denagard 10% Premix / 100 kg bodyweight).
Withdrawal Periods
Withdrawal periods according to national registrations.
Special Precautions and Warnings
Do not administer the ionophore anticoccidials salinomycin, monensin or narasin to poultry and pigs receiving therapeutic doses of DENAGARD. Pigs and poultry should not receive products containing ionophores during or for at least seven days before or after treatment with DENAGARD.
Formulations and Packages
DENAGARD 2% and 10% Premix is available in bags of 1kg (10% Premix only), 5 kg and 25kg bags.
Product Availability
Please note that not all products listed within this site may be available in all countries. Also, prescribing information and indications for products may differ from country to country, so please consult your local veterinarian for local prescribing and any other information you may be interested in.
Locations
Headquartered in Basel, Switzerland, and present in almost 40 countries, Novartis Animal Health employs approximately 2,900 associates worldwide.
Partnerships
Novartis collaborates with many companies and academic institutions to develop new products, acquire platform technologies, and access new markets.
Related Info
Visit our international Denagard website to learn more about one of the most potent antibiotics against the key enteric and respiratory infections affecting pigs and poultry..
Denagard Website
(International)