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Deramaxx® (Deracoxib)
Product information on this website is for Non-U.S. residents only and is provided by Novartis Animal Health Inc. for general purposes only. Many veterinary products listed are available upon prescription only, and not all such products may be available in all countries. The product information is not intended to provide complete medical information. SHOULD YOUR ANIMAL HAVE A MEDICAL CONDITION, PROMPTLY SEE YOUR OWN VETERINARIAN. WE DO NOT OFFER PERSONALIZED MEDICAL DIAGNOSIS OR ANIMAL-SPECIFIC TREATMENT ADVICE. You should always obtain complete medical information about your veterinary product prescription (including their beneficial medical uses and possible adverse effects) by discussing the appropriate use of any veterinary product directly with the prescribing veterinarian.
Veterinary professionals may obtain complete medical information from the product's information leaflet. Information on these products may vary by country. Animal owners and veterinarians should check with local medical resources and regulatory authorities for information appropriate to their country. In addition, current regulations in many countries limit (or even prohibit in some instances) the ability of Novartis Animal Health Inc. to provide information and/or to respond directly to questions regarding its prescription products. Novartis Animal Health Inc., however, will respond to inquiries from and provide information to your qualified health care professional in accordance with local regulations.
Description
Product Type
Oral tablets indicated for the control of pain and inflammation associated with osteoarthritis in dogs; and for the control of postoperative pain and inflammation associated with orthopedic surgery in dogs greater than or equal to four pounds (1.8 kg).
Description and Composition
Oral, beef flavored tablets of 3 strengths are available:
DERAMAXX 25, 75 and 100 contain 25.00 mg, 75.00 mg 100.00 mg deracoxib, respectively. (Approved strengths vary by country)
Properties
Deracoxib, the active ingredient of DERAMAXX, is a coxib class non-narcotic, non-steroidal, cyclooxygenase-inhibiting anti-inflammatory drug (NSAID). DERAMAXX tablets do not inhibit COX-1 based on in vitro studies using cloned canine cylcooxygenase at label doses. The clinical relevance of this in vitro data has not been shown.
Indications
DERAMAXX Chewable Tablets are indicated for the control of pain and inflammation associated with osteoarthritis in dogs; and for the control of postoperative pain and inflammation associated with orthopedic surgery in dogs greater than or equal to four pounds (1.8 kg).
Dosage and Administration
DERAMAXX is administered orally at a dose of 1 - 2 mg/kg as a single daily dose for the indication of control of pain and inflammation associated with osteoarthritis in dogs. DERAMAXX is administered at a dose of 3-4 mg/kg as a single daily dose for the indication of control of postoperative pain and inflammation associated with orthopedic surgery in dogs greater than or equal to four pounds (1.8 kg), not to exceed 7 days.
Since DERAMAXX tablet bioavailability is greatest when taken with food, postprandial administration is preferable. However, DERAMAXX tablets have been shown to be effective under both fed and fasted conditions; therefore, they may be administered in the fasted state if necessary.
Special Precautions and Warnings
All dogs should undergo a thorough history and physical examination before the initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data prior to, and periodically during, administration of any NSAID is recommended.
The use of DERAMAXX tablets with other anti-inflammatory drugs, such as NSAIDS or corticosteroids, should be avoided.
Formulations and Packages
DERAMAXX tablets are available as 25 mg, 75 mg and 100 mg round, brownish, half-scored tablets in 30 and 90 count bottles.
U.S. Residents
This is an international website and is intended for residents outside the US.
If you are a Consumer or Veterinarian in the USA and have questions about our products, please call:
Novartis Technical Product Services Group
1-800-637-0281
Risk Factors
Is My Dog at Risk for Osteoarthritis?
Product Availability
Please note that not all products listed within this site may be available in all countries. Also, prescribing information and indications for products may differ from country to country, so please consult your local veterinarian for local prescribing and any other information you may be interested in.