Panolog® (Nystatin, Thiostrepton, Neomycin, Triamcinolone acetonide)
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Ointment for the topical treatment of acute and chronic otitis externa and dermatological disorders in cats and dogs.
Description and Composition
PANOLOG is an ointment containing: (per ml)
100.000 U Nystatin (INN)
- 2.500 U Thiostrepton (INN)
- 2.5 mg Neomycin (INN) as sulphate
- 1.0 mg Triamcinolone acetonide
in a non –irritating oily vehicle: Plastibase®.
PANOLOG ointment contains the antibiotics neomycin and thiostrepton for broad spectrum activity against gram positive and gram negative bacteria, nystatin, which inhibits yeast and yeast-like fungi (including Malassezia), and triamcinolone acetonide, a steroid with anti-inflammatory, anti-pruritic and anti-allergic activity.
PANOLOG ointment is indicated for the treatment of acute and chronic otitis externa (including those cases complicated by Malassezia spp. and Candida albicans), anal gland infection in dogs and cats, interdigital cysts in dogs, and dermatitis, including eczematous dermatitis, contact dermatitis and seborrhoeic dermatitis. It is indicated in the management of dermatological disorders characterized by inflammation, particularly those caused, complicated or threatened by bacterial or yeast infections, and other conditions susceptible to corticoid-antibacterial-antifungal therapy. It is useful as an adjunct in the treatment of dermatitis due to parasitic infection.
Clinical trials have demonstrated that Panolog ointment is effective in the treatment of the ear mite, Otodectes cynotis, in the dog and cat. The mode of action is uncertain as none of the components in Panolog ointment have recognised acaricidal activity.
Dosage and Administration
Frequency of administration is dependent on the severity of the condition. For mild inflammation, application may range from once daily to once a week; for severe conditions PANOLOG ointment may be applied two or three times daily, if necessary. Frequency of treatment may be decreased as improvement occurs.
Otitis: Clean ear of impacted cerumen. Inspect canal and remove any foreign bodies such as grass awns, ticks etc.). Instill three to five drops of the ointment. It may be advisable to instill two to three drops of a local anaesthetic into the ear prior to cleaning.
Anal glands and cystic lesions: drain and fill the gland or cyst with ointment
Other dermatological disorders: clean affected areas, removing any encrusted discharge or exudates. Apply the ointment sparingly in a thin film.
Special Precautions and Warnings
Panolog ointment is not indicated for the treatment of deep abscesses or deep seated infections, such as those of the lymphatic system, for which parenteral therapy is indicated.
Standard care is recommended to be certain that the tympanic membrane is not ruptured before instilling any medication into the ear.
During a course of treatment the situation should be reviewd frequently by close veterinary supervision.
Panolog has been well tolerated. Cutaneous reactions attributable to its use have been rare. Sensitivity to neomycin may occur. If redness, irritation or swelling persist or increase, discontinue use.
Systemic glucocorticoid side effects are rare following topical use, however systemic absorption of triamcinolone through topical application and by licking may occur, particularly when used over large areas or for extended periods of time. Therefore animals should be monitored closely for signs of polydipsia, polyuria and increased weight gain.
Use during pregnancy or lactation
Use in pregnant animals should be avoided. Administration in early pregnancy in known to have caused foetal abnormalities in laboratory animals. Administration in late pregnancy may cause early parturition or abortion.
Formulations and Packages
PANOLOG is available in 7.5 ml and 15 ml tubes and dropper bottles, and in 100 ml bottles.
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Novartis Technical Product Services Group
Atopic dermatitis(AD) is one of the most common skin diseases of dogs.
Used for the treatment of chronic manifestations of atopic dermatitis in dogs.
Please note that not all products listed within this site may be available in all countries. Also, prescribing information and indications for products may differ from country to country, so please consult your local veterinarian for local prescribing and any other information you may be interested in.
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